Ian Holloway has made four changes to the side that were defeated by Burton Albion at the weekend
He has elected to throw in James Perch, Ryan Manning, Jamie Mackie and Conor Washington at the expense of Grant Hall, Michael Doughty, Kazenga LuaLua and Idrissa Sylla.
New signings Sean Goss and Luke Freeman are joined on the bench by the returning Jordan Cousins and Mike Petrasso.
Newcastle United: Darlow; Yedlin, Lascelles, Clark, Dummett; Ritchie, Shelvey, Hayden, Gouffran; Perez, Murphy.
Substitutes: Sels, Hanley, Gamez, Lazaar, Ameobi, Diame, Mitrovic.
QPR: Smithies; Furlong, Onouoha, Perch, Lynch, Bidwell; Wszolek, Luongo, Manning; Mackie, Washington.
Substitutes: Ingram, Freeman, Cousins, Gosss, Doughty, Petrasso, LuaLua.
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